Obscurity factor: 9
This embattled sitcom had many plot and cast changes in its short two season run. It began with James Whitmore as the chief of surgery in a Washington DC hospital. When that didn't work, they brought in Paul Lynde and Sudie Bond and the setting became a private clinic owned by Bond and run by Lynde. For the last few episodes, it became a public hospital again and featured Lynde and Alice Ghostly as his sister, a nurse at the hospital. The only cast member to last the whole series was Cleavon Little. Part of the problem the series had was scheduling - it was up against the ratings powerhouse Maude. Another problem was that it didn't really fit in with the trend in television at the time. Several seasons earlier it might have had more success, but in the age of social consciousness comedies like All in the Family and Maude, this show seemed a trifle tone deaf.
Above is part one of the episode "Healer Man" which was from the last incarnation of the series featuring Ghostly. It was uploaded to YouTube by jknuttel.
Obscurity factor: 9 (very hard to find, not on DVD, available on YouTube)